Danville Museums 125 S 2nd St Ephraim McDowell House in Danville, Kentucky historical, descendent, and tourist information. On Christmas morning, 1809, Dr. McDowell began his historic operation. The ovarian tumor he removed from Mrs. Crawford weighed twenty-two and one-half pounds. The surgery was performed without benefit of anesthetic or antisepsis, neither of which was known to the medical profession at the time. Mrs. Crawford's surgery was successful. Danville KY Museums Mc Dowell House and Apothecary www.mcdowellhouse.com ephraim mcdowell Ephraim McDowell McDowell House Dr. John Bell Dr. Alexander Humphries medical history frontier danville Danville Kentucky ovarian tumor jane todd crawford abdominal surgery apothecary landmark historical McDowell ephraim mcdowell Ephraim McDowell McDowell House Dr. John Bell Dr. Alexander Humphries medical history frontier danville Danville Kentucky ovarian tumor jane todd crawford abdominal surgery apothecary landmark historical McDowell Business Reviews Mc Dowell House and Apothecary Testimonials